1. Botanical abẹlẹ & Ibile Lo
Ewe Mulberry (Morus alba L.) ni:
1-Deoxynojirimycin (DNJ)(0.1-0.3%) - Agbara -glucosidase inhibitor
Awọn flavonoids(quercetin, isoquercitrin)
Polyphenols(chlorogenic acid, rutin)
Awọn igbasilẹ itan:
Compendium ti Materia Medica ṣe akosilẹ -awọn ohun-ini diabetic rẹ
Orile-ede Japanese "aisan suga{0} tii idena"
2. Key irinše & Mechanisms
2.1 Glucose Metabolism Regulation
2.2 Bioactives & Awọn ibi-afẹde
|
Ẹya ara ẹrọ |
Akoonu |
Àfojúsùn |
Ipa |
|
1-Deoxynojirimycin |
0.1-0.3% |
Aala fẹlẹ oporoku |
Dinku gbigba glukosi |
|
Quercetin-3-glucoside |
1.2-2.5% |
AMPK ọna |
Ṣe ilọsiwaju ifamọ insulin |
|
Chlorogenic acid |
0.8-1.5% |
PPAR iyipada |
Ṣe idiwọ gluconeogenesis ẹdọ |
3. Didara Standards
3.1 Ijeri
Maikirosikopi: Iwa ti kii - awọn irun glandular pẹlu awọn ipilẹ ti o wú
TLC itẹka: 5 pato to muna beere
HPLC iyegeTi o tobi ju tabi dọgba si 0.1% DNJ (boṣewa Pharmacopoeia)
3.2 Modern pato
Pharmacopoeia Kannada: Lapapọ awọn flavonoids Ti o tobi ju tabi dọgba si 1.5%
Standard Japanese: DJ Tobi ju tabi dọgba si 0.15%
Ilana EU: Awọn iṣẹku ipakokoropaeku<0.01ppm
4. Isẹgun Ẹri
4.1 Àtọgbẹ Management
Iru II DM: 1200mg fun ọjọ kan dinku HbA1c nipasẹ 0.8-1.2%
Àrùn àtọ̀gbẹ: NNT{0}} lati dena lilọsiwaju àtọgbẹ
4.2 Metabolic Anfani
Ilana ọra: 15-20% triglyceride idinku
Isakoso iwuwo: 2-3cm idinku iyipo ẹgbẹ-ikun (ọsẹ 12)
5. Imudara lilo
5.1 Dosing nwon.Mirza
Ipilẹ: 300mg (ounjẹ iṣẹju 30 ṣaaju -)
lekoko: 600mg + chromium konbo
5.2 Awọn akojọpọ Amuṣiṣẹpọ
Gymnema sylvestre: Ṣe ilọsiwaju yomijade insulin
Alfa-lipoic acid: Ṣe ilọsiwaju lilo glukosi agbeegbe
Probiotics: Modulates ikun -ipo pancreas
6. Awọn ero aabo
Ewu ti hypoglycemia: Nilo ibojuwo pẹlu antidiabetics
Awọn alaisan abẹ: Da ọsẹ kan duro ṣaaju -op
GI ifamọ: Bẹrẹ pẹlu kekere abere
7. Itọsọna Aṣayan Ọja
Ẹya Awọn ọja Ere:
Aami DJ akoonu
Iwadi iwọn otutu kekere{{0}
Eru irin igbeyewo iroyin
Awọn ọrọ to wọpọ:
Iyipada pẹlu awọn oniruuru DNJ kekere{{0}
Sintetiki DJ agbere
8. Iwadi Furontia
Ifun microbiota: Mu Akkermansia lọpọlọpọ
NAFLD ilọsiwaju: Idilọwọ awọn sẹẹli stelate ẹdọ
Awọn ilana itusilẹ duro{{0}: Awọn iṣẹ ṣiṣe DNA pẹ
Ipari Imọ
Iyọkuro ewe Mulberry n pese:
1️⃣ Opo -ilana ibi-afẹde(ẹdọ+ẹdọ+ awọn ara agbeegbe)
2️⃣ Adayeba ailewu(itan agbara ọdun 2000)
3️⃣ Okeerẹ ti iṣelọpọ anfani(glukosi+ lipids+iwuwo)
